Officials said attackers drove the ambulance past a police checkpoint into a street near offices of the European Union and Afghanistan's High Peace Council.
The attack took place a week after five heavily armed Taliban suicide bombers stormed Kabul's Intercontinental Hotel in a highly secured part of the city, killing at least 22 people.
"Our priority and focus right now is to help those in need and provide the best treatment for those wounded", he wrote.
The Resolute Support mission remains focused on defeating the insurgents in Afghanistan, the commander of the mission said today, following a terrorist bombing in Kabul. The spokesman for Kabul police, Basir Mujahid, confirmed to Efe that "a suicide bomber with a auto loaded with explosives tried to penetrate complex [of ministry], but was identified by police at entrance and detonated vehicle". The country's security forces in particular have suffered heavy casualties at the hands of the Taliban, who want to re-impose their strict version of Islamic law in the country.
"Indiscriminate attacks against civilians are grave violations of human rights and global humanitarian law and can never be justified", he added.
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He spoke of how his government's recent tax cuts plan was helping the U.S. economy by "giving workers higher pay" and promoting investment.
After a recent visit to Afghanistan, the U.S.'s ambassador to the United Nations, Nikki Haley, said the aggressive policy was working and that peace talks were closer than ever.
He also expressed sympathy with the Afghan government and people and the families of the victims.
"It was a large explosion that did not escape the attention of any of our people in Kabul", a statement from Central Command said.
It was the second successful Taliban attack in a week on high security targets in the city. On Wednesday a US drone slammed into Pakistani tribal territory that borders Afghanistan killing two Haqqani commanders, according to Pakistani officials, who deny providing organized camps for their safety. This year, they insist, the Taliban will begin to lose territory again.
Earlier on this day in the Afghan capital, a powerful explosion happened, which killed more than 60 people and injured more than 150 people.