It was the ideal outing for Barcelona after ninth-placed Girona had taken a shock early lead on their first-ever visit to Nou Camp.
Suarez crashed a shot against a post early in the second half and Bono's save denied Messi his hat trick before Coutinho showcased his talents with a superb curling effort to put Barcelona 5-1 ahead in the 66th minute. Coutinho is developing an understanding with the front two and was involved in a lovely move where Messi sent him through before he squared the ball to Luis Suarez, who eventually went onto score a hattrick.
Barcelona head coach Ernesto Valverde had hinted at changes, but Messi and Suarez both started, while Coutinho and Ousmane Dembele replaced Paulinho and Andres Iniesta.
Semedo, a €30.5 million (RM146.9 million) signing from Benfica last July, has been in and out of the team due to competition from Sergi Roberto and made his 11 league start in the 6-1 thrashing of Girona on Saturday but was forced off in the 86 minute. "It sounds easy but it is not", said Barca coach Ernesto Valverde.
Dos jugadores de Boca se bajaron del viaje a Perú
El ex Lanús padece una sinovitis postraumática rodilla izquierda , mientras que Licha sufre de una contractura recto anterior izquierdo .
Messi then took centre-stage, scoring a delightful goal, to give Barcelona a 2-1 lead when he skipped past three defenders to score. "I'm very happy with Ronaldo's gesture".
"Just when a player seems to have done everything, he goes and surprises you". After there is this gesture of Cristiano for Karim.
"They are players who have to help us and who are already doing it, each with their own characteristics". The reigning champions' title hopes are all but over, with Real 14 points adrift of Barca, but a run of four straight wins has ended any worries of missing out on a Champions League spot.