The pre-match build-up has been dominated by questions over whether it would be beneficial to finish second in the group and avoid the top half of the draw, packed with heavyweights Brazil, France, Argentina, Uruguay and Portugal, until a potential final.
While Group H winners Colombia are seen as tricky opponents, Southgate said he had had no preference about who his team would line up against in the last 16.
At this World Cup though, conventional wisdom has been turned on its head.
"We have got to think that through", he said when asked if he might field a weaker side against Belgium.
"We´ve not won a knockout game since 2006".
So now, they are ready to face anyone, after Japan next Monday. The captain, leading the Golden Boot race with five goals after his hat-trick against Panama, has scored 13 times in his last nine internationals and, certainly, a reason for England fans to be cheerful is him.
"Kevin Spacey es un sobón" — Guy Pierce
En noviembre, el consejo de administración del teatro anunció que 20 hombres habían presentado demandas contra Spacey . Las tres nuevas acusaciones fueron informadas por primera vez por TMZ y confirmadas por la policía a Variety .
But Southgate did concede he would probably make some changes for a clash that neither side needs to win.
Belgium manager Roberto Martinez told reporters winning was not a priority for his team and is expected to rest players, which has only fuelled England fans' confidence.
Kane and Co. will be playing against Colombia, and manager Gareth Southgate is calling it the "biggest knockout game for a decade".
"People will say that will only be the right decision if we win but it was the right decision because we could potentially be going into another match that could go into extra time and risking players we didn't need to risk". That would mean we top the group.
"We have no idea who, when or where we will play in the next round but we are pleased that we're in the next round".
Goal-nado - Harry Kane has been scoring goals for fun. - The big talking point before this game was whether the team who finished second in the group would have an "easier" run to the semi-final of the tournament.
Flemish daily De Standaard wrote: "The Red Devils showed they were sportsmanlike and ambitious and that they are afraid of no one - not even a quarter-final against Brazil".
"On the pitch, we were just thinking of having fun", said 21-year-old attacking midfielder Youri Tielemans, who forced England goalkeeper Jordan Pickford into an excellent save with a long-range effort in the first half.
Aliou Cisse´s Senegal will attempt to succeed where the rest of their continental rivals failed, with Egypt, Morocco, Nigeria and Tunisia all out.