Despite pressure from the left and members of the #MeToo movement, U.S. Sen.
A conservative who served in President George W. Bush's White House, Kavanaugh will replace the court's swing vote, Justice Anthony Kennedy, and will likely move the court to the right for decades to come.
The Senate voted 50-48 in favour of confirming Brett Kavanaugh's appointment following a week of drama, including an interruption of the final vote by protesters shouting 'Shame on you!' and 'I do not consent!'
Manchin said he had reservations about Kavanaugh because of the sexual misconduct allegations against him "and the temperament he displayed in the hearing".
"Kavanaugh's confirmation is devastating as unresolved questions remain about his human rights record, including in relation to the US government's use of torture and other forms of ill treatment, such as during the Central Intelligence Agency detention program", Daphne Eviatar, Amnesty International USA's director of security with human rights, said in a statement.
Flake, whose term ends in 2018, decided not to run for re-election.
But Republican Senate Majority Leader Mitch McConnell, claimed the confrontation would turn out to his party's advantage. Mr Trump will be able to campaign on the back of an important victory, but commentators will be watching closely how the Kavanaugh affair affects women voters.
Elizabeth Warren, who voted against Kavanaugh yesterday along with U.S. Sen.
At just 53 years old, Kavanaugh could conceivably serve on the court - now evenly divided between liberals and conservatives - for decades, tilting it to the right.
Stats: India's 100th Test win at home is their biggest in history
You felt for debutant Shermon Lweis when Ashwin unleashed a carrom ball which left the tailender completely bamboozled. Meanwhile, Prithvi Shaw, Virat Kohli, and Ravindra Jadeja scored centuries to help India in posting a big total.
It reflects a high water mark of the Trump presidency: Republican control of the White House, the Senate, the House of Representatives and the judiciary's top court.
Democratic Senator Chuck Schumer said: "Republicans knew he was very flawed, but once he was nominated, it became a steam roller".
Kavanaugh's nomination blew up into a personal and political drama when university professor Christine Blasey Ford accused him of sexually assaulting her in the upstairs bedroom of a home in a wealthy suburb of Washington in 1982.
Warren is using the Kavanaugh confirmation as a main talking point as she considers a run for president in 2020.
Kavanaugh's confirmation process has laid bare the partisan gridlock on Capitol Hill and the political polarization of America just a month before midterm elections.
Protestors started gathering around 4 p.m.in the designated area outside the Expocentre, waving signs expressing their opinions about President Trump, Sec. of State and gubernatorial candidate Kris Kobach, and the confirmation of Brett Kavanaugh to the Supreme Court. Ford had testified that she was 100 percent certain Kavanaugh was the man who assaulted her. Kavanaugh forcefully and tearfully denied the accusations in a fiery opening statement and was openly hostile toward Democrats as they questioned him about the alleged assault and his drinking habits.
Republican Lisa Murkowski of Alaska, a fellow moderate and a friend of Collins, is the only Republican who has indicated she will vote no.
Kavanaugh's nomination was protested from the beginning by Democrats and liberal activists who oppose the judge's conservative record on key issues including abortion, environmental protection, and presidential powers.
Kavanaugh will be sworn in on Saturday "so that he can begin to participate in the work of the Court immediately", according to a statement on the Supreme Court's website.
Gary Cameron / Reuters Rep. John Lewis (D-Ga.) speaks at a rally before the five conservatives on the Supreme Court struck down Section 5 of the Voting Rights Act in the Shelby County v. Holder case.