The financier and political consultant is set to compete alongside several other notable figures, including actor Joey Lawrence, former WWE wrestler Natalie Eva Marie, comedian Tom Green, singer Kandi Burruss and former Olympic swimmer Ryan Lochte. The guests will live together for 24 hours a day for four weeks, with at least one being "evicted" every week.
The last of the 12 cast members remaining at the end of the season will win $250,000.
Julie Chen Moonves will return as host of the show.
The Mooch won't be Big Brother's first ex-Trumper contestant.
More than 6 million already hit by flu, CDC says
In the past, the CDC has waited until the end of the season to release estimates of how many people have been affected by flu. Anyone with flu complications or symptoms should seek medical treatment with an anti-viral drug, officials said.
The CBS announcement comes a year after Omarosa Manigault-Newman, the "Apprentice" alum and former White House aide, appeared on the show and held forth about her time in the Trump administration.
She wrote a tell-all about her time at the White House called "Unhinged" and released a tape of then-Chief of Staff John Kelly firing her.
At one point last season, Omarosa gave a shoutout to Scaramucci while on the show, and he returned the favor in a February 2018 tweet.
Mooch was sacked after just six days in President Donald Trump's White House after a profanity-laced tirade aimed at leakers and White House chief of staff Reince Priebus, as reported by The New Yorker.
Stepping back into the spotlight, Scaramucci, who has been working at his investment firm since his White House stint, attended the Golden Globes earlier this month.